Glucose control with HCL vs. SAP in outpatients with T1D

09 mayo 2022

This material shows results from a real-life study in outpatients with type 1 diabetes (T1D), Hybrid Closed Loop (HCL) system improved glucose control compared with Sensor-Augmentes Pumps (SAP) with telehealth monitoring. The key takeaways are, that for T1D, outpatient initiation of insulin pump is safe with adapted education programs and telehealth monitoring, which results to be a tool for improvement in glucose control, and that this pump initiation is compatible with HCL systems which provide the largest improvements in glucose control.

This matters because attaining glycemic targets to avert diabetic complications remain challenging. The starting points of this study are, that it is a single-center open-label study that assessed clinical outcomes, it had three categories, first-time pump users, current CSII users changing to SAP with stand-alone CGM or SAP and predictive low glucose suspend capacities and CGM, and HCL users. The primary objective of the study was to mean change in HbA1c between initial visit and after 3 months of follow-up based on treatment effect, and as a secondary objective, it was expected to maintain percent glucose values in the target range of 3.9 mmol/L (70-180 mg/dL) and glycemic variability.